Department of Obstetrics and Gynaecology
The overall aim of this project is to identify new mechanisms responsible for the functions of immune cells. We aim to:
- Define the functions of immune cells at the maternal-foetal interface
- Characterise the key signals immune cells use to recognise tumours
- Determine the pathways responsible for the outcome of cell transplantation
I work closely with Research Associates and PhD students on this overall project and give occasional training. Prior to this position i was a Research Technician for the Institute of Metabolic Sciences. Where i worked for the principal investigator, Dr Sue Ozanne on a projects exploring the early programming of appetite, type 2 diabetes, breast cancer and ageing.
Boulenouar S, Doisne JM, Sferruzzi-Perri A, Gaynor LM, Kieckbusch J, Balmas E, Yung HW, Javadzadeh S, Volmer L, Hawkes DA, Phillips K, Brady HJ, Fowden AL, Burton GJ, Moffett A, and Colucci F (2016). The residual innate lymphoid cells in NFIL3-deficient mice supoort suboptimal maternal adaptations to pregnancy. Immunol. 7:43.
Kieckbusch J, Balmas E, Hawkes DA, and Colucci F (2015). Disrupted p110δ signalling dysregulated maternal immune cells and increases fetal mortality in mice. Cell Rep. 13(12): 2817-2828.
Doisne JM, Balmas E, Boulenouar S, Gaynor LM, Kieckbusch J, Gardner L, Hawkes DA, Barbara CF, Sharkey AM, Brady HJ, Brosens JJ, Moffett A, and Colucci F (2015). Composition, development and function ofuterine innate lymphoid cells. J. Immunol. 195(8): 3937-3945.