The Department of Obstetrics and Gynaecology comprises a very talented and multidisciplinary team of researchers, technicians and clinicians. Research in our department falls into two broad areas. The first covers the use of large population databases to identify key predictive features associated with human pregnancy. Research is also focused on perinatal control of maternal and fetal smooth muscle contractility; clinical research interest in predicting pregnancy complications such as intra-uterine growth restriction, preterm labour and perinatal death.
The second uses genomics to identify key regulatory genes involved in the development of blood vessels in all tissues but focusing on those in the endometrium and placenta, in healthy tissue and in ectopic endometrium and cancer. This interdisciplinary work involves complex teams of molecular and cellular biologists, anatomists, mathematicians, bioinformaticians, statisticians and clinician-scientists.
The Department of Obstetrics and Gynaecology is a proud supporter of the Athena Swan initiative, our clinical school is a silver award holder.
Recent Seminars and Presentations
Professor Gordon Smith recently attended the Global Obstetric Update 2019 (GOU) conference held in Melbourne, Australia 28-30 November 2019. Gordon delivered two presentations:
‘Science Corner – bacteria and viruses lurking in the placenta as the cause of major pregnancy complications’
‘Special Oration – 35 weeks and a small for gestational age fetus is suspect. What do we do?’
The Department of Obstetrics and Gynaecology has programmes of basic, translational and clinical research addressing the determinants of pregnancy complications.
We also often collaborate on studies at The Rosie Hospital.
News
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function
A new study published in PLoS Genetics by Miguel Constância’s group shows that a gene called Igf2, which produces a…
Abnormal placental CD8+ T‐cell infiltration
A new study published in the Journal of Physiology by Susanne Lager and colleagues shows that lesions and accumulation of…
Study predicts fetal growth restriction using metabolomics
A study by Ulla Sovio, Gordon Smith and colleagues, published in Nature Medicine, has identified metabolites predictive of fetal growth…
O&G session at Science Festival cancelled
Unfortunately due to precautions around the Coronavirus, a number of events for the Science Festival have been cancelled including the…
5 March Visiting speaker – Nancy McBride
Metabolomic prediction of pregnancy-related disorders Speaker: Nancy McBride, Doctor of Philosophy Student, University of Bristol Time: Thursday 5th of March…