Elin Bernson
Visiting Postdoctoral Researcher
In my work, I aim to develop a deeper understanding of the woman’s body and diseases associated with it.
At leisure, I enjoy being outdoors sailing, skiing and hiking with my family and friends.
Research interests
• Natural killer cell regulation
• Ovarian cancer
• Immunotherapy
Publications
Highlighted:~
Brwa Ali Hussein, Alexander Hallner, Lovisa Wennström, Mats Brune, Anna Martner, Kristoffer Hellstrand, Elin Bernson, Fredrik Bergh Thorén. Impact of NK Cell Activating Receptor Gene Variants on Receptor Expression and Outcome of Immunotherapy in Acute Myeloid Leukemia. Frontiers in Immunology (2021);796072.
DOI: 10.3389/fimmu.2021.796072
Alexander Hallner, Elin Bernson, Brwa Ali Hussein, Frida Ewald Sander, Mats Brune, Johan Aurelius, Anna Martner, Kristoffer Hellstrand, Fredrik Bergh Thorén. The HLA-B -21 dimorphism impacts on NK cell education and clinical outcome of immunotherapy in acute myeloid leukemia. Blood (2019);133(13):1479-1488.
Elin Bernson, Alexander Hallner, Frida Ewald Sander, Malin Nicklasson, Malin S Nilsson, Karin Christenson, Ebru Aydin, Jan-Åke Liljeqvist, Mats Brune, Robin Foà, Johan Aurelius, Anna Martner, Kristoffer Hellstrand, Fredrik Bergh Thorén. Cytomegalovirus serostatus affects autoreactive NK cells and outcomes of IL-2-based immunotherapy in acute myeloid leukemia. Cancer Immunology Research (2018);6(9):1110-1119.
Elin Bernson, Alexander Hallner, Frida Ewald Sander, Oscar Wilsson, Olle Werlenius, Anna Rydström, Roberta Kiffin, Mats Brune, Robin Foà, Johan Aurelius, Anna Martner, Kristoffer Hellstrand, Fredrik Bergh Thorén. Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia. Leukemia (2017);31(12):2552-2559.
Research summary
My research focuses on how NK cell regulation impact on outcome during disease. During my doctoral studies, I focused on natural killer (NK) cell function in myeloid leukaemia, and how KIR-HLA interactions impact on the NK cell functionality during immunotherapy treatment.
After my PhD defence, I engaged in regulation of NK cells in an inflammatory context. My current project aims to understand how NK cells are regulated in ovarian cancer, and how this regulation may impact on the outcome of the disease. The research also aims to elucidate potential immunotherapeutic approaches as novel therapies for ovarian cancer patients.
Contact
Room 107, University Department of Obstetrics & Gynaecology, Level 2, The Rosie Hospital
Phone: +44 (0)1223 336880