In a recent collaborative work between Miguel Constância and Susan Ozanne groups and published in the journal Nature Metabolism, the authors reviewed the importance of studying sex differences in response to pre-conception or early-life exposures that could lead to the known sexual dimorphism in susceptibility to poor metabolic health in adulthood. The role of biological […]
Presentation now live
As part of the Cambridge Reproduction SRI Early Researchers Seminar Series, Giulia Avelino presented and gave an overview of her PhD study. If you missed her talk, the video recording is now available.
International Day of the Midwives
On Thursday 5 May midwives across the world will be celebrating International Day of the Midwife 2022. This time of celebration will reflect on progress in midwifery over the past 100 years. To celebrate this important day our Women’s Health Under the Microscope team have released their first video. An interview with Amy Sutton-Cole, Lead […]
Metabolomic identification of a novel, externally validated predictive test for gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a condition where high blood sugar develops during pregnancy. GDM is one of the major preventable causes of stillbirth. Currently in the UK, women are selected for diagnostic testing for GDM based on risk factors such as obesity. Better methods for the prediction of GDM are needed. Ulla Sovio and […]
Giulia Avellino presenting
Giulia is presenting 17 March as part of the Early Researchers Seminar Series for Cambridge Reproduction SRI. Her talk is entitled “Acetyl-CoA metabolism and human trophoblast differentiation.” Further details can be found here.
The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth
In a new study led by Miguel Constância published in the journal Developmental Cell, Ionel Sandovici and colleagues report the identification of a key signal that a fetus uses to control its supply of nutrients from the placenta. In mammals, the fetus receives nutrients and oxygen via blood vessels in the placenta, a temporary, specialized […]
Women’s Health Under the Microscope – a public engagement initiative
We are launching our new public engagement initiative “Women’s Health Under the Microscope”. With this project, we aim to communicate science and spread knowledge about research focusing on women’s health, as well as raise awareness on the topic and break stigmas around it. On a weekly basis, we will on social media platforms share content […]
A maternal serum metabolite ratio predicts large for gestational age infants at term
Large size at birth is associated with complications in the mother and the baby. To complement their work on the metabolomics of fetal growth restriction (FGR) (Nature Medicine, 2020), Ulla Sovio and colleagues analysed their previously developed metabolite ratio in relation to large for gestational age (LGA) infants born at term. In the study published […]
Amy Sutton-Cole presenting
Amy is presenting as part of the programme for the Cambridge Reproduction SRI monthly forum taking place Friday 5 November 2 – 3:45pm. Presentation title is “Recruiting to a clinical research study during a global pandemic: how the Pregnancy Outcome Prediction Study 2 (POPS2) adapted”. For full programme details and how to join visit the […]
Dafina Angelova presenting
Dafina is presenting 21 October as part of the Early Researchers Seminar Series for Cambridge Reproduction SRI. Her talk is entitled “Single cell transcriptomic analysis elucidates the course of murine trophoblast stem cell differentiation.” Click here for full details.
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