Evgeniya (Zhenya) Shmeleva and Francesco Colucci sum up the knowns of natural killer cells and infections during pregnancy in their paper published today in the Mucosal Immunology journal – the official publication of the Society for Mucosal Immunology. Shmeleva EV, Colucci F. Maternal natural killer cells at the intersection between reproduction and mucosal immunity. Mucosal […]
A study led by Ulla Sovio and Gordon Smith at the Department of Obstetrics and Gynaecology, published in The American Journal of Obstetrics and Gynecology, identified new biomarkers predictive of early term spontaneous labour. The team performed a secondary analysis of the Pregnancy Outcome Prediction study. They found that slowing of fetal growth velocity detected […]
The uterus of mammalian species (including humans and model organisms such as mice) contains many immune cells that are critical for a successful pregnancy. In a new paper published in the journal Immunity, Norman Shreeve and colleagues from Francesco Colucci’s group at the Department of Obstetrics and Gynaecology, together with their collaborators, studied the role […]
We are delighted to share that our Head of Department, Professor Gordon Smith has taken on the role of Ambassador for Sands (Stillbirth and neonatal death charity) to help drive the charity’s ground-breaking work to save babies’ lives. His internationally recognised research is looking for better ways to predict problems in pregnancy so babies and mothers […]
Dr Irving Aye is delighted to be hosting the Cambridge Reproduction SRI Early Researchers Seminar Series taking place Thursday 8 April 2021 at 1pm. Presentations: High dimensional analysis of human placental macrophages and the identification of novel emerging populations during pregnancy Anna Appios (Pathology) Changes in placental mitochondrial function are associated with fetal weight variation […]
Congratulations to Professors Gordon Smith and Steve Charnock-Jones on the publication of their paper in Nature. The study is the first high-resolution survey of the genomic architecture of the human placenta, revealing specific patterns of mutation that are commonly found in childhood cancers In the first study of the genomic architecture of the human placenta, […]
Congratulations to Dr Francesco Colucci and co-authors whose article entitled “Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy” has featured in the Editors’ Highlights. Selection was made as the paper was recognised as some of the “most exciting Immunology work” published in Nature Communications.
Cambridge Reproduction SRI is delighted to sponsor the panel ‘Sexual Health and Reproduction’ at the conference Queer Migrations: Transnational Sexualities in Theory and Practice: PANEL 3: Sexual Health and Reproduction Friday 27 November 2020, 4 – 5:30pm, online Chair: Julieta Chaparro Buitagro (University of Cambridge) Marcin Smietana (University of Cambridge), ‘LGBTQ Reproductive Migrations and Queer […]
A new study published in PLoS Genetics by Miguel Constância’s group shows that a gene called Igf2, which produces a protein similar to insulin, and is active only on the chromosome inherited from the father, is key for the control of pancreas size and function. Within the pancreas, Igf2 is mostly active in a specific […]
A new study published in the Journal of Physiology by Susanne Lager and colleagues shows that lesions and accumulation of specific immune cells in the placental tissue are more common in fetal growth restriction and pre‐eclampsia than in uncomplicated pregnancies. Read the full paper now.