Steve Charnock-Jones

Dr. D.S.Charnock-Jones
Tel:+44 (0)1223 336875
E-mail: dscj1@cam.ac.uk

Dr. D. Stephen Charnock-Jones is a University Reader in the Department of Obstetrics & Gynaecology.

Directs the research of the Reproductive Molecular Research Group and Gene Networks Research Group.

Cindrova-Davies T, Sanders DA, Burton GJ*, Charnock-Jones DS* (2011)

Soluble FLT1 sensitizes endothelial cells to inflammatory cytokines by antagonizing VEGF receptor-mediated signalling.

Cardiovascular Research 89: 671-679. PubMed Abstract

Affara M, Dunmore BJ, Sanders DA, Johnson N, Print CG*, Charnock-Jones DS*. (2011)

MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms.

BMC Genomics 2011; 12: 43. PubMed Abstract

Yamaji M, Bielby H, Licence D, Cheng CW, Cook E, Smith SK, Print CG, Charnock-Jones DS. (2010)

VEGF-A loss in the haematopoietic and endothelial lineages exacerbates age-induced renal changes.

Microvasc Res 2010; 80: 372-383. PubMed Abstract

Mokhtar NM, Cheng CW, Cook E, Bielby H, Smith SK, Charnock-Jones DS. (2010)

Progestin regulates chemokine (C-X-C motif) ligand 14 transcript level in human endometrium.

Mol Hum Reprod 2010; 16: 170-177. PubMed Abstract

Belteki G, Kempster SL, Forhead AJ, Giussani DA, Fowden AL, Curley A, Charnock-Jones DS*, Smith GC*. (2010)

Paraoxonase-3, a putative circulating antioxidant, is systemically up-regulated in late gestation in the fetal rat, sheep, and human.

J Clin Endocrinol Metab 2010; 95: 3798-3805. PubMed Abstract

Burton GJ, Yung HW, Cindrova-Davies T, Charnock-Jones DS. (2009)

Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset preeclampsia.

Placenta 2009; 30 Suppl A: S43-48. PubMed Abstract

Yung HW, Calabrese S, Hynx D, Hemmings BA, Cetin I, Charnock-Jones DS*, Burton GJ*.(2008)

Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction.

Am J Pathol 2008; 173: 451-462. PubMed Abstract

Cheng CW, Smith SK, Charnock-Jones DS.(2008)

Transcript profile and localization of Wnt signaling-related molecules in human endometrium.

Fertil Steril 2008; 90: 201-204. PubMed Abstract

Yung HW, Korolchuk S, Tolkovsky AM, Charnock-Jones DS*, Burton GJ*. (2007)

Endoplasmic reticulum stress exacerbates ischemia-reperfusion-induced apoptosis through attenuation of Akt protein synthesis in human choriocarcinoma cells.

FASEB J 2007; 21: 872-884. PubMed Abstract

Cindrova-Davies T, Yung HW, Johns J, Spasic-Boskovic O, Korolchuk S, Jauniaux E, Burton GJ*, Charnock-Jones DS*. (2007)

Oxidative Stress, Gene Expression, and Protein Changes Induced in the Human Placenta during Labor.

Am J Pathol 2007; 171: 1168-1178. PubMed Abstract

Cindrova-Davies T, Spasic-Boskovic O, Jauniaux E, Charnock-Jones DS, Burton GJ. (2007)

Nuclear factor-kappa B, p38, and stress-activated protein kinase mitogen-activated protein kinase signaling pathways regulate proinflammatory cytokines and apoptosis in human placental explants in response to oxidative stress: effects of antioxidant vitamins.

Am J Pathol. 2007 May;170(5):1511-20. PubMed Abstract

Cheng CW, Bielby H, Licence D, Smith SK, Print CG & Charnock-Jones DS (2007)

Quantitative cellular and molecular analysis of the effect of progesterone withdrawal in a murine model of decidualization.

Biol Reprod. 2007 May;76(5):871-83.

* denotes joint Senior Author